The potential for Cerenkov luminescence imaging of alpha-emitting radionuclides
نویسندگان
چکیده
منابع مشابه
Harnessing the power of radionuclides for optical imaging: Cerenkov luminescence imaging.
Over the past several years, nuclear imaging modalities such as PET and SPECT have received much attention because they have been instrumental not only in preclinical cancer research but also in nuclear medicine. Yet nuclear imaging is limited by high instrumentation cost and subsequently low availability to basic researchers. Cerenkov radiation, a relativistic physical phenomenon that was disc...
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We demonstrate feasibility of endoscopic imaging of Cerenkov light originated when charged nuclear particles, emitted from radionuclides, travel through a biological tissue of living subjects at superluminal velocity. The endoscopy imaging system consists of conventional optical fiber bundle/ clinical endoscopes, an optical imaging lens system, and a sensitive low-noise charge coupled device (C...
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UNLABELLED The development of novel multimodality imaging agents and techniques represents the current frontier of research in the field of medical imaging science. However, the combination of nuclear tomography with optical techniques has yet to be established. Here, we report the use of the inherent optical emissions from the decay of radiopharmaceuticals for Cerenkov luminescence imaging (CL...
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Introduction: The choice of optimal radionuclides for radioimmunotherapy depends on several factors, especially the radionuclide and antibody. The dosimetric characteristics of a non-internalizing and an internalizing monoclonal antibody (MAb) labeled with beta emitting radionuclides were investigated. Methods: Using Geant4-DNA Monte Carlo simulation, we ...
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Introduction: After the lead poisoning outbreak came to light in Zamfara State, Nigeria, people living near gold mines were worried about environmental safety, especially drinking water quality. This study examined the gross alpha and gross beta activity concentrations in groundwater in different locations of Anka, Zamfara State, Nigeria, to measure the possible radiation dose and potential hea...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2012
ISSN: 0031-9155,1361-6560
DOI: 10.1088/0031-9155/57/3/771